How to Setup Hand Sanitizer Factory

By Admin 13 Jul 2020

Hand sanitizers can be manufactured on Form 25 of Drugs and Cosmetics Rules and under Pharma License. This factory can manufacture following chemical based hand sanitizers are:

  • Ethyl Alcohol, Glycerine & Hydrogen Peroxide sanitizer
  • Isoproyl Alcohol, n-Propanol, Ethyl-Hexadecyl-Dimethyl Ammonium-Ethyl Sulphate Liquid.
  • Chlohexidine Gluconate, Cetrimide & Ethanol Solution for Hand Rub


Criteria for selection of Land


  • Land must be in Govt. Approved industrial area
  • If land is in Municipal area, NOC is needed from concern Municipal Corporation.


Area Required


  • Plot Size 500 sqmt.
  • Covered Area 10,000 sqft.


Raw Material Store Rooms


  • Dedusting Area
  • Quarantine Area
  • Sampling Area
  • Under test Area
  • Approved Area
  • AC area
  • Dispensing Area
  • Day store


Other required stores


  • Bottle Store
  • Label box Store
  • Finished Goods store


Laboratory Rooms


  • Chemical Lab
  • Instrument Lab
  • Stability Lab
  • Control Sample
  • Document Room



  • Hand Sanitizer Mixer

This is the equipment used for mixing the ingredients. This can be a Vacuum Emulsifier, High Shear Mixer or a Powder-liquid Disperser Mixer which can make small to large batches of hand sanitizer solution.


This is a machine used for accurately filling container bottles for hand sanitizers. You have several options such as Liquid Filling Machines and Viscous Liquid Filling Machines.


  • Hand Sanitizer Capping Machine

An automated machine, capping machines can automatically cap bulk hand sanitizer containers in a matter of an hour. You may have several options such as Screw Capping Machines, Rotary Vacuum Screw Capping Machine

  • Hand Sanitizer Labeling Machine

Labeling machines can accurately put a brand or emboss a name on your containers. A variety of options include Pressure Sensitive Labeler, Optical Laser Printing Machine, Inject Printing Machine.


Types of Hand Sanitizer can be manufactured:


  • Liquid Alcohol Based Hand Sanitizers

Alcoholics hand sanitizer generally contain alcohols or isopropanols as the active ingredient that killed germs and bacteria. The contents of alcohols in the hand sanitizing products usually ranges between 60% and 95%, which is considering by FDA to be effectively killing germ and bacteria, including corona viruses, MRSA, and Ecoli.


Alcohol based hand sanitizers are considering to be more potent and rapid in killing germ, virus and bacteria, compared to alcohols-free hand sanitizer. However, alcohol based hand sanitizer could be worrisome to some consumer for its risks of flammability intoxications, and damages to the users’ skins.


  • Gel Alcohol-Based Hand Sanitizers

Experiments have been done to examine the efficiency of liquid hand sanitizers and gel hand sanitizer. In general, liquid hand sanitizer better than gel hand sanitizers.


Scientists proved that liquid hand sanitizer in liquid form reacts sooner compared to gel hand sanitizers. On average, it took the liquid ones 15 seconds and the latter the double of the time to act.


  • Foam Alcohol-Based Hand Sanitizer

The foam hand sanitizers are more economical compared to liquid or gel ones, for the airy and incompact texture of the products. In addition, foam is more clinging to hands and will not easily drop, which could cause damage to the floor or the carpet.


  • Spray Alcohol-Based Hand Sanitizer

Like foam hand sanitizers, there are some arguments regarding the economic efficiency of spray hand sanitizers. Some argue that spray is wasteful compared to liquid and gel since the drops might miss your hands or be deflected into the air when spraying, some hold the opposite opinion saying that spray is more cost-effective, for the liquid is condensed by the nozzle and thus delivers fewer doses, although this might lead to the dilution of active ingredients.


No quantifiable experiment has been made to testify each of the arguments, we suggest the buyers choose the products based on their own judgment.


  • Antiseptics Alcohol-Free Hand Sanitizer   

Alcohol-free sanitizers often contain benzalkonium chloride, as its main ingredient in killing bacteria and viruses.